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How can radon affect people's health?

Almost all risk from radon comes from breathing air with radon and its decay products. Radon decay products cause lung cancer. The health risk of ingesting radon, in water for example, is dwarfed by the risk of inhaling radon and its decay products. They occur in indoor air or with tobacco smoke. Alpha radiation directly causes damage to sensitive lung tissue. Most of the radiation dose is not actually from radon itself, though, which is mostly exhaled. It comes from radon's chain of short-lived solid decay products that are inhaled on dust particles and lodge in the airways of the lungs. These radionuclides decay quickly, producing other radionuclides that continue damaging the lung tissue.

There is no safe level of radon--any exposure poses some risk of cancer. In two 1999 reports, the National Academy of Sciences (NAS) concluded after an exhaustive review that radon in indoor air is the second leading cause of lung cancer in the U.S. after cigarette smoking. The NAS estimated that 15,000-22,000 Americans die every year from radon-related lung cancer.

When people who smoke are exposed to radon as well, the risk of developing lung cancer is significantly higher than the risk of smoking alone.

The NAS also estimated that radon in drinking water causes an additional 180 cancer deaths annually. However almost 90% of those projected deaths were from lung cancer from the inhalation of radon released to the indoor air from water, and only about 10% were from cancers of internal organs, mostly stomach cancers, from ingestion of radon in water.